Research Paper Volume 15, Issue 12 pp 5713—5733

Figure 6. Comparison of genomic mutations in LGG samples from the low and high MAGOH subgroups in the TCGA dataset. (A, B) Circos plots of low and high MAGOH subtypes of LGG, showing the amplifications and deletions of chromosomes, with boxplots showing that copy number amplifications and deletions were lower in the low than in the high MAGOH subgroup. (C, D) Waterfall plots showing mutated genes in the low (C) and high (D) MAGOH subgroups. (E, F) Association of MAGOH expression and TMB levels in patients with LGG. (G, H) Association between TMB level and patient prognosis (G) and the differential prognostic value of TMB level in the low and high MAGOH subtypes of patients with LGG (H). ^*P < 0.05, ^**P < 0.01, ^***P < 0.001.