Research Paper Volume 15, Issue 15 pp 7513—7532

Figure 4. NORAD-knockout aggravates SI-induced mitochondrial ROS and C3 expression level in vivo. Mitochondrial ROS and AMD markers were detected in wild-type mice and NORAD knockout mice treated with sodium iodate. (A–F) Flow cytometry was used to detect the mitochondrial ROS levels in the eyes, heart, lungs, liver, brain, and kidneys of mice on day 8 after SI injection. n=3, *P < 0.05, **P < 0.01. (G) mRNA expression of AMD markers in eyes of the mouse through qRT-PCR. n = 3, *P < 0.05, **P < 0.01.