Research Paper Volume 15, Issue 20 pp 10915—10937

The Saccharomyces cerevisiae acetyltransferase Gcn5 exerts antagonistic pleiotropic effects on chronological ageing

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Figure 8. The working model demonstrating the contradictory roles of Gcn5 in CLS regulation. AcCoA: acetyl-CoA. UDPG: UDP-glucose ? and ?? denote respectively the anti-ageing and pro-ageing hallmarks to be determined. Arrow: activation; bar: inhibition.