Research Paper Volume 15, Issue 20 pp 11131—11151

Figure 7. Triptolide repressed tumor growth in A2780 xenografts. (A) The tumor volume curve. (B) Tumor samples were shown. (C) Tumor weight. (D) Body weight of mice. (E) H&E staining was used to observe the toxic and side effects of the TPL. (F, G) The expressions of Ki67, PCNA, Gli1, Gli2, and Cleaved Caspase 3 in tumor tissues of each group were detected by IHC. Quantitative data are presented in graph (G). Scale bar: 100 μm. * p < 0.05, ** p < 0.01 and *** p < 0.001 vs. control.