Research Paper Volume 15, Issue 20 pp 11268—11285

Integrated bulk and scRNA sequence identified anoikis-related diagnostic biomarkers and potential association with immune infiltration in type A aortic dissection

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Figure 2. Identification of DEGs and functional annotation for TAAD patients. (A) Principal component analysis showing transcriptome signatures sorted TAAD and control cohorts into two clusters. (B) Volcano plots showing the DEGs between TAAD and HC cohorts with p<0.05 and absolute log (FC) >1. (C) The GO functional analysis of upregulated and downregulated DEGs. (D, E) The KEGG functional analysis of up-regulated and downregulated signatures. (F) The GSEA indicating the functional difference between TAAD and HC cohorts.