Research Paper Volume 15, Issue 20 pp 11313—11330
Role of NF-κB pathway in kidney renal clear cell carcinoma and its potential therapeutic implications
Figure 4. (A) Co-expression analysis showed that 21 NF-κB-related genes were associated in tumor tissues, with R-value indicating correlation size, red indicating positive correlation, and blue indicating negative correlation, p<0.05 was statistically significant. The regression relationship of NFκB1 with the remaining genes is represented by a scatterplot. (B) Based on three clusters, the IC50 predictions of 12 common tumor-targeted drugs for drugs with KIRC cells were analyzed. (C) Association of acetylation-related genes (HDAC and SIRT) and classical tumor family genes with NF-κB scores.