Research Paper Volume 15, Issue 20 pp 11532—11545

Indoxyl sulfate induced frailty in patients with end-stage renal disease by disrupting the PGC-1α–FNDC5 axis

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Figure 6. Treatment with RSV ameliorated IS-induced PGC-1α–FNDC5 dysfunction. (A) Protein levels of PGC-1α, FNDC5, myoD, and actin were examined using Western blotting. (B) Graphic abstract.