Research Paper Volume 15, Issue 20 pp 11588—11610

Immunobiological signatures and the emerging role of SPP1 in predicting tumor heterogeneity, malignancy, and clinical outcomes in stomach adenocarcinoma

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Figure 1. Immune cell correlation analysis and weighted gene co-expression network analysis (WGCNA). (A) Correlation analysis of immune cell populations in normal and tumor samples, with negative correlations in blue and positive correlations in red. (B) Detailed immune cell correlation analysis. (C) Sample clustering to detect groups with more than 75 samples. (D) WGCNA co-expression analysis showing which module each gene belongs to. (E) Clinical correlation analysis of each module to observe the correlation between modules and immune cells, with blue representing negative correlation and red representing positive correlation.