Research Paper Volume 15, Issue 21 pp 12225—12250

Plumbagin has an inhibitory effect on the growth of TSCC PDX model and it enhances the anticancer efficacy of cisplatin

class="figure-viewer-img"

Figure 11. Relative expression of AXL, SCG5, VOPP1, DCBLD2, DRAM1, DUSP1, AQP5, BLNK in the four treatment groups. Treatment groups referred to PDX tumors harvested from mice. (A) The expression of differential genes in four groups of PDX models by RT-qPCR. (B) The expression of differential genes in four groups of PDX models by Western blotting. The quantitative data are shown as the mean ± SD of 3 independent experiments. ***P < 0.001; **P < 0.01; *P < 0.05; −, no statistical difference.