Phoenixin-20 ameliorates Sevoflurane inhalation-induced post-operative cognitive dysfunction in rats via activation of the PKA/CREB signaling

Jing Zhang; Zhao Wang; Kun Cong; Jun Qi; Lining Sun

doi:doi:10.18632/aging.205177

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Research Paper Volume 15, Issue 24 pp 14666—14676

Phoenixin-20 ameliorates Sevoflurane inhalation-induced post-operative cognitive dysfunction in rats via activation of the PKA/CREB signaling

Figure 8. Phoenixin-20 activated the PKA/CREB signaling in the hippocampus tissue of Sev-treated rats. (A) Protein level was determined using western blots. Analysis of (B) PKA; (C) CREB; (D) Protein level of p-CREB (n=6, *, **, P<0.05 or 0.01 vs. sham group; †, ††, P<0.05 or 0.01, vs. Sev group).