Research Paper Volume 15, Issue 22 pp 13287—13311
Molecular characteristics and clinical implications of serine/arginine-rich splicing factors in human cancer
Figure 4. DNA methylation, m6A modification and miRNA regulations of SRSFs. (A) Heatmap demonstrating the correlation between DNA methylation level within promoters and SRSFs mRNA expression in each cancer type. (B) m6A-SRSFs protein-protein interaction network showing m6A regulators interacted with SRSFs frequently. (C) miRNA–SRSF interaction network and heatmap demonstrating miRNA-SRSF pairs displayed different correlation directions in different cancer contexts. Red represents a positive correlation, and green represents a negative correlation.