Research Paper Volume 15, Issue 24 pp 14733—14748
Anoikis regulator GLI2 promotes NC cell immunity escape by TGF-β-mediated non-classic hedgehog signaling in colorectal cancer: based on artificial intelligence and big data analysis
Figure 6. Independent cohort verification of ARG-based AI model. (A) Gene expression heatmap. (B, C) Hazard ratio of hubgenes in male cohort and female cohort in GSE39582. (D) Prognosis differences in AI model identified ARG subpopulations, in which overall survival (p = 0.021) and recurrence free survival (p = 00.019) are different in whole cohort, also different in (E) male cohort while no significance in (F) female cohort. (G) Immune cell infiltration in ARG subpopulations in GSE39582 cohort. (H–K) Immunity checkpoints expression features in ARG subpopulations.