Research Paper Volume 15, Issue 24 pp 15287—15323
Integrated analysis of bulk RNA-seq and single-cell RNA-seq reveals the function of pyrocytosis in the pathogenesis of abdominal aortic aneurysm
Figure 1. Visualization of the DEGs in AAA Combined Datasets. (A) Volcano map of differential expression gene analysis of the difference between the AAA group and the CON group. Red represents significantly up-regulated genes and blue represents significantly down-regulated genes. (B) Thermogram of the expression values of 30 up-regulated and 30 down-regulated genes in the AAA group compared with the CON group. Red means high gene expression, blue means low gene expression. (C, D) Bubble map of differential gene GO functional enrichment analysis (C) and KEGG pathway enrichment (D). Bubbles represent the number of enriched genes, the larger the enrichment genes, the darker the color, the more significant the P-value, and the darker the color, the more significant the difference. Abbreviations: AAA: abdominal aortic aneurysm; CON: control; GO: Gene Ontology; KEGG: Kyoto Encyclopedia of Genes and Genomes.