Research Paper Volume 16, Issue 1 pp 246—266

The potential value of the Purinergic pathway in the prognostic assessment and clinical application of kidney renal clear cell carcinoma

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Figure 2. (A) Correlation analysis between Purinergic gene methylation and mRNA expression. The color bar indicates the correlation coefficient's magnitude, and the dots' size represents the comparison between the P-value and 0.05. (B) Analysis of the difference in the degree of methylation of the Purinergic gene in different tumor tissues and normal tissues. The color bar indicates the degree of difference, and the size of the dots represents the comparison between the P-value and 0.05. (C) Correlation analysis between the degree of methylation of the Purinergic gene and survival risk. Red dots represent high survival risk, blue dots represent low survival risk, and the size of the dots represents the comparison between the P-value and 0.05. (D) Relationship between Purinergic genes and classical cellular pathways. A represents activation, and I represent suppression.