Research Paper Volume 16, Issue 1 pp 568—592

Immune landscape and heterogeneity of cervical squamous cell carcinoma and adenocarcinoma

class="figure-viewer-img"

Figure 6. Verification of the levels of immunocytes infiltration and inhibitory immune checkpoints expression in collected CSCC and ADC samples. (A) Representative images of CD8A (T cells) and CD20 (B cells) in collected CSCC patients. (B) Representative images of CD8A (T cells) and CD20 (B cells) in collected ADC patients. (C, D) Statical charts displayed that CD8A (T cells) and CD20 (B cells) were more abundant in CSCC compared to ADC patients in our collected samples. (E, F) Representative staining of T cells (CD3/CD4/CD8) and inhibitory immune checkpoints (PD1/PD-L1/CTLA-4) in CSCC and ADC patients, respectively. (G, H) Statical charts displayed that T cells (CD3/CD4) and some immune inhibitory checkpoints (PD1/PD-L1/CTLA4) were more abundant in CSCC compared to ADC patients in our collected samples. * P <0.05; ** < P <0.01, *** P <0.001; ns: not significant.