Research Paper Volume 15, Issue 24 pp 15557—15577

Exploring the effect and mechanism of Aloin A against cancer cachexia-induced muscle atrophy via network pharmacology, molecular docking, molecular dynamics and experimental validation

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Figure 11. Effect of Aloin A on muscle histology in mice bearing lung tumor. (A) Representative images of hematoxylin and eosin (H&E) of transversal sections of the muscle. Scale bars: 50 μm. (B) The quantification of cross-sectional area (CSA) in muscle fibers. (C) Relative frequency of muscle fibers. The values are shown as the mean ± SEM (n = 3). ***P < 0.001 vs. the control group. ###P < 0.001 vs. the LLC group.