Research Paper Volume 16, Issue 2 pp 1845—1859
Activation of Notch-1 signaling pathway in macrophages to secrete PD-L1 and regulate cytotoxicity of CAR-T cells in diffuse large B-cell lymphoma
Figure 6. Imaging of the effect of mouse tumor transplantation and myeloid-specific knockout Notch-1 on lymphoma progression and scale plot of CD4+/CD8+. (A) Results of mouse tumor transplantation and imaging; (B) Fluorescence area in each group; (C) Ratio diagram of CD4+/CD8+. (WT group vs. KO group; WT + lymphoma cell group vs. KO + lymphoma cell group; WT + lymphoma cell + IXA4 group vs. KO + lymphoma cell + IXA4 group; **P < 0.01, nsP > 0.05; N = 3).