Research Paper Volume 16, Issue 6 pp 5091—5107

GSG2 promotes thyroid cancer via stabilizing AURKB and activating AKT pathway

class="figure-viewer-img"

Figure 4. GSG2/AURKB participates in the development of thyroid cancer. (AC) The alterations in cell proliferation (A), migration (B) and apoptosis (C) were evaluated in B-CPAP and TPC-1 cells with indicated lentiviruses through Celigo cell counting assay, wound-healing assay and flow cytometry analysis. Results were presented as mean ± SD. * P < 0.05, ** P < 0.01, ***P < 0.001; NC(OE+KD): Control, AURKB+NC(KD): AURKB overexpression, AURKB+shGSG2: AURKB overexpression+ GSG2 downregulation.