Research Paper Volume 16, Issue 6 pp 5224—5248

Development and validation of a novel biomarker panel for Crohn’s disease and rheumatoid arthritis diagnosis and treatment

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Figure 5. Immuno-infiltration analysis of core genes in CD. (A) Heatmap of immune cell type scores based on ssGSEA. (B) Differential analysis of the sum of immune scores based on ssGSEA. (C) Differential analysis of immune cell type scores based on ssGSEA. (D) Correlation heatmap of core genes and immune cell types. (E) Differential analysis of immune scores based on ESTIMATE. (F) Differential analysis of ESTIMATE scores. Abbreviation: ssGSEA: single-sample gene set enrichment analysis. *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001.